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Takeshi Maruo Selected Research

Phenolsulfonphthalein (Phenol Red)

2/2005Progesterone receptor modulator CDB-2914 down-regulates proliferative cell nuclear antigen and Bcl-2 protein expression and up-regulates caspase-3 and poly(adenosine 5'-diphosphate-ribose) polymerase expression in cultured human uterine leiomyoma cells.
2/2005Gonadotropin-releasing hormone antagonist cetrorelix down-regulates proliferating cell nuclear antigen and epidermal growth factor expression and up-regulates apoptosis in association with enhanced poly(adenosine 5'-diphosphate-ribose) polymerase expression in cultured human leiomyoma cells.
4/2004Progesterone down-regulates insulin-like growth factor-I expression in cultured human uterine leiomyoma cells.
8/2002p53 Tumor suppressor protein content in human uterine leiomyomas and its down-regulation by 17 beta-estradiol.

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Takeshi Maruo Research Topics

Disease

25Leiomyoma (Uterine Fibroids)
09/2011 - 03/2002
9Endometriosis
01/2007 - 02/2004
7Neoplasms (Cancer)
10/2008 - 08/2002
4Menorrhagia
09/2011 - 11/2003
3Death (Near-Death Experience)
03/2021 - 08/2015
3Heart Failure
12/2018 - 01/2004
3Cardiovascular Diseases (Cardiovascular Disease)
12/2017 - 02/2011
3Myoma
11/2010 - 11/2003
3Threatened Abortion
12/2007 - 06/2002
2ST Elevation Myocardial Infarction
03/2021 - 12/2017
2Myocardial Infarction
03/2021 - 08/2015
2Aortic Valve Stenosis (Aortic Stenosis)
07/2017 - 01/2014
2Thrombosis (Thrombus)
08/2015 - 01/2011
2absence of Vagina
01/2009 - 05/2003
2Atherosclerosis
11/2008 - 01/2005
2Carcinoma (Carcinomatosis)
10/2008 - 04/2003
2Premature Obstetric Labor (Premature Labor)
12/2007 - 06/2002
2Endometrial Neoplasms (Endometrial Cancer)
05/2007 - 10/2006
2Pre-Eclampsia (Preeclampsia)
04/2007 - 01/2002
2Hemorrhage
01/2007 - 11/2002
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2004 - 04/2003
1Ischemic Stroke
03/2021
1Sudden Death
07/2017
1Vascular System Injuries
01/2017
1Hypotension (Low Blood Pressure)
01/2016
1Myocarditis (Carditis)
01/2012
1Thrombocytopenia (Thrombopenia)
01/2012
1Hypersensitivity (Allergy)
01/2011
1Hypertension (High Blood Pressure)
11/2008
1Left Ventricular Dysfunction
11/2008

Drug/Important Bio-Agent (IBA)

15Proteins (Proteins, Gene)FDA Link
04/2008 - 01/2002
13Progesterone Receptors (Progesterone Receptor)IBA
11/2010 - 04/2004
11ProgesteroneFDA LinkGeneric
11/2010 - 08/2002
9Epidermal Growth Factor (EGF)IBA
11/2010 - 11/2003
8asoprisnilIBA
09/2011 - 04/2006
7ulipristalIBA
09/2011 - 02/2005
7Proliferating Cell Nuclear Antigen (PCNA)IBA
11/2010 - 03/2002
7Messenger RNA (mRNA)IBA
03/2008 - 03/2002
7Insulin-Like Growth Factor I (IGF-1)IBA
12/2007 - 06/2002
5Matrix Metalloproteinases (MMPs)IBA
11/2010 - 04/2006
5Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
05/2010 - 11/2003
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2010 - 09/2006
4AdrenomedullinIBA
11/2010 - 04/2003
4CollagenIBA
11/2010 - 03/2008
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2010 - 11/2003
4Gonadotropin-Releasing Hormone (GnRH)FDA Link
04/2006 - 03/2002
4Phenolsulfonphthalein (Phenol Red)IBA
02/2005 - 08/2002
3Metalloproteases (Metalloproteinases)IBA
11/2010 - 03/2008
3Levonorgestrel (Plan B)FDA LinkGeneric
11/2010 - 11/2003
3Estrogens (Estrogen)FDA Link
05/2010 - 04/2006
3Protein Isoforms (Isoforms)IBA
05/2010 - 12/2004
3ErbB Receptors (EGF Receptor)IBA
12/2007 - 01/2007
3Caspase 3 (Caspase-3)IBA
12/2007 - 02/2005
3DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
12/2007 - 04/2003
3Bovine Serum AlbuminIBA
02/2005 - 04/2004
3Estrogen ReceptorsIBA
12/2004 - 04/2004
2Heparin (Liquaemin)FDA LinkGeneric
01/2012 - 06/2005
2Tissue Inhibitor of Metalloproteinase-2IBA
11/2010 - 04/2008
2LigandsIBA
05/2010 - 02/2007
2EnzymesIBA
05/2010 - 04/2008
2INTERCEEDIBA
01/2009 - 05/2003
2Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA
04/2008 - 03/2008
2deoxyuridine triphosphateIBA
12/2007 - 04/2003
2Transforming Growth Factor beta (TGF-beta)IBA
12/2007 - 07/2006
2Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
10/2006 - 04/2006
2AndrogensIBA
07/2006 - 01/2003
2Estradiol (Delestrogen)FDA LinkGeneric
07/2006 - 08/2002
2Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA
02/2006 - 02/2005
2DNA (Deoxyribonucleic Acid)IBA
02/2005 - 02/2004
2LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA
02/2005 - 03/2002
2IGF Type 1 Receptor (IGF 1 Receptor)IBA
01/2005 - 04/2004
2Estriol (Epiestriol)IBA
01/2005 - 01/2005
2Gonadal Steroid Hormones (Sex Hormones)IBA
11/2003 - 08/2002
1LDL CholesterolIBA
03/2021
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
03/2021
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
12/2017
1human NPPA protein (carperitide)IBA
01/2016
1CreatinineIBA
01/2016
1Sirolimus (Rapamycin)FDA Link
08/2015
1Pharmaceutical PreparationsIBA
09/2011
1omega-Chloroacetophenone (Mace)IBA
02/2011
1PolymersIBA
01/2011
1Collagen Type III (Type III Collagen)IBA
11/2010
1Brain Natriuretic Peptide (Natrecor)FDA Link
11/2008
1Cisplatin (Platino)FDA LinkGeneric
10/2008
1Dihydrotachysterol (AT 10)IBA
04/2008
1Tissue Inhibitor of Metalloproteinase-1IBA
04/2008
1Matrix Metalloproteinase 14 (MT1-MMP)IBA
04/2008

Therapy/Procedure

4Therapeutics
01/2005 - 05/2003
2Percutaneous Coronary Intervention
03/2021 - 12/2017
2Transcatheter Aortic Valve Replacement
01/2017 - 01/2014
2Stents
08/2015 - 01/2011
2Laparotomy
01/2007 - 06/2004
2Cesarean Section (Caesarean Section)
01/2004 - 05/2003
1Patient Readmission
12/2018
1Renal Dialysis (Hemodialysis)
07/2017
1Catheters
01/2017
1Oral Administration
09/2011
1Hysterectomy
09/2011
1Neoadjuvant Therapy
10/2008